CalcoSin® Ultra is a dietary supplement containing potassium and magnesium citrates and plant extracts (phyllanthus, stonebreaker, birch, pellitory-of-the-wall, and restharrow), in 20 sachets to dissolve in water. It is intended for adults predisposed to stone formation who want to support urinary tract health, alongside proper hydration and following their doctor's advice. It may support urinary well-being, but it does not prevent or treat stones and is not a substitute for treatments or specialist advice.
- 1 sachet per day, dissolved in water
- Two mineral citrates and 5 plant extracts
- Pack of 20 sachets, equivalent to 20 days of use
Kidney stones and urinary stone disease: what they are
Stones are solid deposits that form in the kidneys when certain substances in urine, such as calcium, oxalate, or uric acid, become too concentrated and crystallize. When the crystals are very small, like grains of sand, they are called urinary gravel. Their formation is encouraged by several factors:
- drinking too little water and having highly concentrated urine;
- consuming too much salt;
- a diet too high in animal protein;
- being overweight and sedentary;
- family history and individual characteristics.
Types of stones: calcium oxalate, uric acid, and others
Stones are classified into different types based on their composition:
- calcium oxalate stones, the most common type;
- calcium phosphate stones;
- uric acid stones, also linked to urinary pH;
- struvite stones, associated with urinary tract infections;
- cystine stones, which are rare and genetic in origin.
Stone analysis and tests prescribed by a urologist or nephrologist help provide guidance tailored to each individual case.
Urinary pH and citrate: why they matter
Citrates, the salts of citric acid, are naturally present in urine. They bind to calcium and make the environment less favorable to the formation of calcium oxalate crystals; urine pH also affects stone formation, particularly uric acid stones. For this reason, European urology guidelines recommend citrate, at doses determined by a doctor, for people with recurrent stones and low urinary citrate levels.
CalcoSin® Ultra provides potassium and magnesium in the form of citrates as nutritional support, alongside proper hydration and a balanced diet. It does not replace prescribed treatments.
Composition per sachet
The table shows the amount of each ingredient in the recommended daily dose.
| Ingredient |
Daily amount |
| Potassium citrate |
1667 mg |
| of which potassium |
600 mg (30% NRV*) |
| Magnesium citrate |
909.1 mg |
| of which magnesium |
100 mg (26.7% NRV*) |
| Total citrates |
1626 mg |
| Phyllanthus (Phyllanthus niruri) dry extract |
300 mg |
| of which tannins |
45 mg |
| Birch dry extract |
200 mg |
| Rustyback |
200 mg |
| Pellitory-of-the-wall |
100 mg |
| Restharrow dry extract |
100 mg |
*NRV: Nutrient Reference Values.
Potassium citrate
It is the main component of the formula. Potassium contributes to normal muscle function, normal functioning of the nervous system, and the maintenance of normal blood pressure.
Magnesium citrate
Completes the mineral component of the formula. Magnesium contributes to electrolyte balance, normal muscle function, and the reduction of tiredness and fatigue.
Plant extracts
The plant extracts complete the formula with naturally derived support for urinary system health:
-
Phyllanthus (Phyllanthus niruri, standardized to 15% tannins), known in South America as chanca piedra: promotes urinary function;
-
Birch (Betula pendula, leaves): promotes urinary function;
-
Rustyback (Ceterach officinarum, leaves): promotes urinary function and the drainage of bodily fluids;
-
Pellitory-of-the-wall (Parietaria officinalis): promotes urinary function and the drainage of bodily fluids;
-
Restharrow (Ononis spinosa, root): promotes the drainage of bodily fluids and has a soothing and emollient effect on the urinary tract.
How to use CalcoSin® Ultra: 1 sachet a day
Dissolve 1 sachet a day in a glass of water. While taking it, it is important to drink enough throughout the day.
Urinary tract supplement in sachets or tablets: which is best for the kidneys?
There is no single best supplement: the choice depends on the type of stone, test results, and current treatments. Those looking for a supplement for kidney stones or urinary tract health will find a wide range of formulas, from sachets to tablets. Before choosing, consider:
- the presence and amounts of mineral citrates;
- the plant extracts they contain;
- the format: sachets, tablets, or capsules;
- the number of sachets in the package, for example 20 or 30;
- any medications you are taking and your kidney function.
Supplements do not replace a doctor's assessment or treatment for kidney stones.
Preventing kidney stones: water and diet
Drinking enough is the most important rule for urinary tract health and preventing kidney stones. European guidelines recommend that people prone to forming stones:
- drink 2.5-3 liters of fluids a day, spread throughout the day;
- limit salt to 4-5 grams a day;
- do not eliminate calcium from your diet, but consume a normal amount;
- moderate your intake of animal protein and eat fruit and vegetables every day;
- maintain a healthy weight and be physically active.
These are basic measures to reduce the risk of further episodes; more specific recommendations depend on the type of stone and test results.
Renal colic: when to seek medical attention
Renal colic occurs when a stone moves along the urinary tract. The most common symptoms are:
- severe pain in the side or back, which may radiate to the abdomen or groin;
- nausea or vomiting;
- blood in the urine;
- frequent urge to urinate or burning.
Seek medical attention right away if you have very severe pain, a fever, chills, or difficulty urinating. Recurrent episodes should also be assessed by a specialist.
What do they do at the emergency room for renal colic?
At the emergency room, pain is treated first, usually with injectable anti-inflammatory drugs. Urine and blood tests are then performed, along with an ultrasound or CT scan to locate the stone. If the stone is small, you may be able to wait for it to pass on its own, sometimes with medication to relax the ureter. If you have a fever or the kidney is blocked, urgent drainage may be needed using a stent or nephrostomy.
How kidney stones are treated
Treatment depends on the size, location, and composition of the stone. The doctor may recommend monitoring stones that can pass on their own, medication, extracorporeal lithotripsy, endoscopic procedures, and metabolic testing for recurrent cases.
Food supplements are not medicines for human use: CalcoSin® Ultra does not dissolve or eliminate existing stones, and breaking up stones is a medical treatment.
Warnings
- Do not exceed the recommended daily dose.
- Food supplements should not be considered a substitute for a varied, balanced diet and a healthy lifestyle.
- Keep out of reach of children under three years of age.
- Do not take if you are using potassium-sparing medicines or have chronic kidney failure without consulting your doctor.
- If you have kidney disease or are undergoing treatment, consult your doctor before use.
- Birch-based preparations are contraindicated in case of aspirin allergy.
Product information: food supplement in 20 sachets
In summary, the key information on the packaging.
- Product: CalcoSin® Ultra, 20 sachets – food supplement, net weight 90 g
- Directions for use: 1 sachet per day
- Brand: GP Nutraceuticals – made in Italy
- Ministry of Health Register of Food Supplements: code no. 86181
Sources
The information on this page is based on the European Association of Urology guidelines, legislation on health claims, and monographs from the European Medicines Agency.
- European Association of Urology. EAU Guidelines on Urolithiasis. uroweb.org
- Regulation (EU) No 432/2012 – permitted health claims. eur-lex.europa.eu
- Italian National Institute of Health – ISSalute. Kidney stones. issalute.it
- European Medicines Agency. Betulae folium. ema.europa.eu
- European Medicines Agency. Ononidis radix. ema.europa.eu
- Ministry of Health. Register of Food Supplements. salute.gov.it
