{"product_id":"calcosin","title":"CalcoSin® Ultra","description":"\u003cdiv style=\"text-align: justify;\"\u003e\n\u003cmeta charset=\"utf-8\"\u003e\n\u003cdiv style=\"text-align: justify;\"\u003e\n\u003cdiv class=\"a-section a-spacing-medium a-spacing-top-small\" id=\"feature-bullets\"\u003e\n\u003cdiv style=\"text-align: justify;\"\u003e\n\u003cdiv style=\"text-align: left;\"\u003e\n\u003cdiv data-cel-widget=\"featurebullets_feature_div\" data-feature-name=\"featurebullets\" class=\"feature\" id=\"featurebullets_feature_div\"\u003e\n\u003cdiv style=\"text-align: justify;\"\u003e\n\u003cdiv data-cel-widget=\"featurebullets_feature_div\" data-feature-name=\"featurebullets\" class=\"feature\"\u003e\n\u003cdiv class=\"flex flex-col text-sm pb-25\"\u003e\n\u003csection data-turn=\"assistant\" data-scroll-anchor=\"true\" data-testid=\"conversation-turn-102\" data-turn-id=\"request-WEB:30424a90-427c-491b-953e-653db3d5ab1d-61\" dir=\"auto\" class=\"text-token-text-primary w-full focus:outline-none [--shadow-height:45px] has-data-writing-block:pointer-events-none has-data-writing-block:-mt-(--shadow-height) has-data-writing-block:pt-(--shadow-height) [\u0026amp;:has([data-writing-block])\u0026gt;*]:pointer-events-auto scroll-mt-[calc(var(--header-height)+min(200px,max(70px,20svh)))]\"\u003e\n\u003cdiv class=\"text-base my-auto mx-auto pb-10 [--thread-content-margin:var(--thread-content-margin-xs,calc(var(--spacing)*4))] @w-sm\/main:[--thread-content-margin:var(--thread-content-margin-sm,calc(var(--spacing)*6))] @w-lg\/main:[--thread-content-margin:var(--thread-content-margin-lg,calc(var(--spacing)*16))] px-(--thread-content-margin)\"\u003e\n\u003cdiv class=\"[--thread-content-max-width:40rem] @w-lg\/main:[--thread-content-max-width:48rem] mx-auto max-w-(--thread-content-max-width) flex-1 group\/turn-messages focus-visible:outline-hidden relative flex w-full min-w-0 flex-col agent-turn\"\u003e\n\u003cdiv class=\"flex max-w-full flex-col gap-4 grow\"\u003e\n\u003cdiv data-turn-start-message=\"true\" class=\"min-h-8 text-message relative flex w-full flex-col items-end gap-2 text-start break-words whitespace-normal outline-none keyboard-focused:focus-ring [.text-message+\u0026amp;]:mt-1\" data-message-model-slug=\"gpt-5-3\" dir=\"auto\" data-message-id=\"f6e1a3c3-1aa9-4d3a-b6c0-f3a23e34d762\" data-message-author-role=\"assistant\" tabindex=\"0\"\u003e\n\u003cdiv class=\"flex w-full flex-col gap-1 empty:hidden\"\u003e\n\u003cdiv class=\"markdown prose dark:prose-invert w-full wrap-break-word light markdown-new-styling\"\u003e\n\u003cp\u003e\u003cstrong\u003eCalcoSin® Ultra\u003c\/strong\u003e is a food supplement containing potassium and magnesium citrates and plant extracts (phyllanthus, stonebreaker, birch, pellitory-of-the-wall and restharrow), in 20 sachets to dissolve in water. It is intended for adults predisposed to stone formation who want to care for their urinary tract health, alongside proper hydration and their doctor's advice. It may support urinary health, but it does not prevent or treat stones and does not replace treatments or specialist advice.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e1 sachet per day to dissolve in water\u003c\/li\u003e\n\u003cli\u003eTwo mineral citrates and 5 plant extracts\u003c\/li\u003e\n\u003cli\u003ePack of 20 sachets, equivalent to 20 days of use\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eKidney stones and urinary stone disease: what they are\u003c\/h2\u003e\n\u003cp\u003eStones are solid formations that develop in the kidneys when certain substances in urine, such as calcium, oxalate or uric acid, become too concentrated and crystallize. When the crystals are very small, like grains of sand, they are called kidney gravel. Their formation is encouraged by several factors:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003edrinking too little water and having highly concentrated urine;\u003c\/li\u003e\n\u003cli\u003econsuming too much salt;\u003c\/li\u003e\n\u003cli\u003ea diet too rich in animal protein;\u003c\/li\u003e\n\u003cli\u003eoverweight and a sedentary lifestyle;\u003c\/li\u003e\n\u003cli\u003efamily history and individual characteristics.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eTypes of stones: calcium oxalate, uric acid and others\u003c\/h3\u003e\n\u003cp\u003eStones are classified into different types according to their composition:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003ecalcium oxalate stones, the most common type;\u003c\/li\u003e\n\u003cli\u003ecalcium phosphate stones;\u003c\/li\u003e\n\u003cli\u003euric acid stones, also linked to urinary pH;\u003c\/li\u003e\n\u003cli\u003estruvite stones, associated with urinary tract infections;\u003c\/li\u003e\n\u003cli\u003ecystine stones, which are rare and genetic in origin.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eStone analysis and tests prescribed by a urologist or nephrologist make it possible to provide advice tailored to each individual case.\u003c\/p\u003e\n\u003ch2\u003eUrinary pH and citrates: why they matter\u003c\/h2\u003e\n\u003cp\u003eCitrates, salts of citric acid, are naturally present in urine. They bind to calcium and make the environment less favorable for the formation of calcium oxalate crystals; urinary pH also affects stone formation, particularly uric acid stones. For this reason, European urology guidelines provide for citrate, at doses determined by a doctor, for people with recurrent stones and low urinary citrate levels.\u003c\/p\u003e\n\u003cp\u003eCalcoSin® Ultra provides potassium and magnesium in the form of citrates as nutritional support, alongside proper hydration and a balanced diet. It does not replace prescribed treatments.\u003c\/p\u003e\n\u003ch2\u003eComposition per sachet\u003c\/h2\u003e\n\u003cp\u003eThe table shows the amount of each ingredient in the recommended daily dose.\u003c\/p\u003e\n\u003ctable\u003e\n\u003cthead\u003e\n\u003ctr\u003e\n\u003cth\u003eIngredient\u003c\/th\u003e\n\u003cth\u003eDaily amount\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003ePotassium citrate\u003c\/td\u003e\n\u003ctd\u003e1667 mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eof which potassium\u003c\/td\u003e\n\u003ctd\u003e600 mg (30% NRV*)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eMagnesium citrate\u003c\/td\u003e\n\u003ctd\u003e909.1 mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eof which magnesium\u003c\/td\u003e\n\u003ctd\u003e100 mg (26.7% NRV*)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eTotal citrates\u003c\/td\u003e\n\u003ctd\u003e1626 mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePhyllanthus (Phyllanthus niruri) dry extract\u003c\/td\u003e\n\u003ctd\u003e300 mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eof which tannins\u003c\/td\u003e\n\u003ctd\u003e45 mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eBirch dry extract\u003c\/td\u003e\n\u003ctd\u003e200 mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eStonebreaker\u003c\/td\u003e\n\u003ctd\u003e200 mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePellitory-of-the-wall\u003c\/td\u003e\n\u003ctd\u003e100 mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eRestharrow dry extract\u003c\/td\u003e\n\u003ctd\u003e100 mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e*NRV: Nutrient Reference Values.\u003c\/p\u003e\n\u003ch3\u003ePotassium citrate\u003c\/h3\u003e\n\u003cp\u003eThis is the main component of the formula. Potassium contributes to normal muscle function, normal functioning of the nervous system, and the maintenance of normal blood pressure.\u003c\/p\u003e\n\u003ch3\u003eMagnesium citrate\u003c\/h3\u003e\n\u003cp\u003eCompletes the formula's mineral component. Magnesium contributes to electrolyte balance, normal muscle function, and the reduction of tiredness and fatigue.\u003c\/p\u003e\n\u003ch3\u003ePlant extracts\u003c\/h3\u003e\n\u003cp\u003eThe plant extracts complement the formula with naturally sourced ingredients to support urinary system wellbeing:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003ePhyllanthus\u003c\/strong\u003e (Phyllanthus niruri, standardised to 15% tannins), known in South America as chanca piedra: supports urinary function;\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBirch\u003c\/strong\u003e (Betula pendula, leaves): supports urinary function;\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eRustyback fern\u003c\/strong\u003e (Ceterach officinarum, leaves): supports urinary function and the drainage of body fluids;\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePellitory-of-the-wall\u003c\/strong\u003e (Parietaria officinalis): supports urinary function and the drainage of body fluids;\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eRestharrow\u003c\/strong\u003e (Ononis spinosa, root): promotes the drainage of body fluids and has a soothing and emollient effect on the urinary tract.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eHow to use CalcoSin® Ultra: 1 sachet a day\u003c\/h2\u003e\n\u003cp\u003eDissolve 1 sachet a day in a glass of water. It is important to drink enough throughout the day while taking it.\u003c\/p\u003e\n\u003ch2\u003eUrinary tract supplement in sachets or tablets: which is best for the kidneys?\u003c\/h2\u003e\n\u003cp\u003eThere is no single best supplement: the choice depends on the type of stone, test results and any ongoing treatments. Those looking for a supplement for kidney stones or the urinary tract will find a wide range of formulations, from sachets to tablets. Before choosing, it is worth considering:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003ethe presence and amounts of mineral citrates;\u003c\/li\u003e\n\u003cli\u003ethe plant extracts included;\u003c\/li\u003e\n\u003cli\u003ethe format: sachets, tablets or capsules;\u003c\/li\u003e\n\u003cli\u003ethe pack size, for example 20 or 30 sachets;\u003c\/li\u003e\n\u003cli\u003eany medications being taken and kidney function.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eSupplements do not replace a doctor's assessment or treatment for kidney stones.\u003c\/p\u003e\n\u003ch2\u003ePreventing kidney stones: water and diet\u003c\/h2\u003e\n\u003cp\u003eDrinking enough is the most important rule for urinary tract health and preventing kidney stones. European guidelines recommend that people prone to forming stones:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003edrink 2.5-3 litres of fluids a day, spread throughout the day;\u003c\/li\u003e\n\u003cli\u003elimit salt to 4-5 grams a day;\u003c\/li\u003e\n\u003cli\u003edo not eliminate calcium from your diet, but consume a normal amount;\u003c\/li\u003e\n\u003cli\u003emoderate animal protein intake and eat fruit and vegetables every day;\u003c\/li\u003e\n\u003cli\u003emaintain a healthy weight and be physically active.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eThese are basic measures to reduce the risk of new episodes; more specific advice depends on the type of stone and test results.\u003c\/p\u003e\n\u003ch2\u003eRenal colic: when to see a doctor\u003c\/h2\u003e\n\u003cp\u003eRenal colic occurs when a stone moves along the urinary tract. The most common symptoms are:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003esevere pain in the side or back, which may radiate to the abdomen or groin;\u003c\/li\u003e\n\u003cli\u003enausea or vomiting;\u003c\/li\u003e\n\u003cli\u003eblood in the urine;\u003c\/li\u003e\n\u003cli\u003efrequent need to urinate or burning.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eSeek medical attention immediately in case of very severe pain, fever, chills or difficulty urinating. Recurrent episodes should also be assessed by a specialist.\u003c\/p\u003e\n\u003ch3\u003eWhat do they do at the emergency department for renal colic?\u003c\/h3\u003e\n\u003cp\u003eAt the emergency department, the pain is treated first, usually with injected anti-inflammatory drugs, followed by urine and blood tests and an ultrasound or CT scan to locate the stone. If the stone is small, you may be able to wait for it to pass on its own, sometimes with medication to relax the ureter; if you have a fever or the kidney is obstructed, urgent drainage may be needed with a stent or nephrostomy.\u003c\/p\u003e\n\u003ch2\u003eHow kidney stones are treated\u003c\/h2\u003e\n\u003cp\u003eTreatment depends on the size, location and composition of the stone. Your doctor may recommend monitoring stones that can pass spontaneously, medication, extracorporeal lithotripsy, endoscopic procedures and metabolic investigations in recurrent cases.\u003c\/p\u003e\n\u003cp\u003eFood supplements are not medicines for human use: CalcoSin® Ultra does not dissolve or remove existing stones, and stone fragmentation is a medical treatment.\u003c\/p\u003e\n\u003ch2\u003eWarnings\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eDo not exceed the recommended daily dose.\u003c\/li\u003e\n\u003cli\u003eFood supplements should not be considered a substitute for a varied, balanced diet and a healthy lifestyle.\u003c\/li\u003e\n\u003cli\u003eKeep out of reach of children under three years of age.\u003c\/li\u003e\n\u003cli\u003eDo not take if you are taking potassium-sparing medicines or have chronic kidney disease without consulting your doctor.\u003c\/li\u003e\n\u003cli\u003eIn case of kidney disease or ongoing treatment, consult your doctor before use.\u003c\/li\u003e\n\u003cli\u003eBirch preparations are contraindicated in cases of aspirin allergy.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eProduct information: food supplement in 20 sachets\u003c\/h2\u003e\n\u003cp\u003eIn summary, the key information on the package.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eProduct: CalcoSin® Ultra 20 sachets – food supplement, net weight 90 g\u003c\/li\u003e\n\u003cli\u003eDirections for use: 1 sachet per day\u003c\/li\u003e\n\u003cli\u003eBrand: GP Nutraceuticals – made in Italy\u003c\/li\u003e\n\u003cli\u003eMinistry of Health Food Supplement Register: code no. 86181\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eWant to know more? Read the \u003cstrong\u003e\u003ca href=\"https:\/\/www.gpnutraceuticals.com\/blogs\/vie-urinarie\/calcoli-renali\"\u003ecomplete guide to kidney stones: symptoms, renal colic, treatments, and what studies say about citrates and supplements\u003c\/a\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003ch2\u003eSources\u003c\/h2\u003e\n\u003cp\u003eThe information on this page is based on European urology guidelines, regulations on health claims and European Medicines Agency monographs.\u003c\/p\u003e\n\u003col\u003e\n\u003cli\u003eEuropean Association of Urology. \u003cem\u003eEAU Guidelines on Urolithiasis.\u003c\/em\u003e \u003ca href=\"https:\/\/uroweb.org\/guidelines\/urolithiasis\"\u003euroweb.org\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eRegulation (EU) No 432\/2012 – authorised health claims. \u003ca href=\"https:\/\/eur-lex.europa.eu\/legal-content\/IT\/TXT\/?uri=CELEX:32012R0432\"\u003eeur-lex.europa.eu\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eNational Institute of Health – ISSalute. \u003cem\u003eKidney stones.\u003c\/em\u003e \u003ca href=\"https:\/\/www.issalute.it\/index.php\/la-salute-dalla-a-alla-z-menu\/c\/calcolosi-renale\"\u003eissalute.it\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eEuropean Medicines Agency. \u003cem\u003eBetulae folium.\u003c\/em\u003e \u003ca href=\"https:\/\/www.ema.europa.eu\/en\/medicines\/herbal\/betulae-folium\"\u003eema.europa.eu\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eEuropean Medicines Agency. \u003cem\u003eOnonidis radix.\u003c\/em\u003e \u003ca href=\"https:\/\/www.ema.europa.eu\/en\/medicines\/herbal\/ononidis-radix\"\u003eema.europa.eu\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eMinistry of Health. \u003cem\u003eFood Supplement Register.\u003c\/em\u003e \u003ca href=\"https:\/\/www.salute.gov.it\/portale\/temi\/p2_6.jsp?area=Alimenti+particolari+e+integratori\u0026amp;id=1267\u0026amp;lingua=italiano\u0026amp;menu=registri\"\u003esalute.gov.it\u003c\/a\u003e\n\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/section\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e","brand":"GP NUTRACEUTICALS","offers":[{"title":"Default Title","offer_id":30405327749219,"sku":"CALCOSIN-ULTRA-BST","price":18.5,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0279\/7735\/1267\/files\/Calcosin_Ultra_2026.jpg?v=1789118314","url":"https:\/\/www.gpnutraceuticals.com\/en-int\/products\/calcosin","provider":"GP NUTRACEUTICALS SRL","version":"1.0","type":"link"}